Most-cited Genetics and Biochemistry papers of 2023, with free PDFs

The 25 most-cited Genetics and Biochemistry research papers published in 2023, ranked by citations in OpenAlex, with their original abstracts and free PDFs where available.

  1. Evolutionary-scale prediction of atomic-level protein structure with a language model
    Zeming Lin, Halil Akin et al. · 2023 · 5,519 citations · Free PDF
  2. UCSF ChimeraX : Tools for structure building and analysis
    Elaine C. Meng, Thomas D. Goddard et al. · 2023 · 4,525 citations
  3. FinnGen provides genetic insights from a well-phenotyped isolated population
    Mitja Kurki, Juha M Karjalainen et al. · 2023 · 4,185 citations · Free PDF
  4. The Gene Ontology knowledgebase in 2023
    Suzi Aleksander, James P. Balhoff et al. · 2023 · 2,687 citations · Free PDF
  5. Fast and accurate protein structure search with Foldseek
    Michel van Kempen, Stephanie S. Kim et al. · 2023 · 2,616 citations · Free PDF
  6. De novo design of protein structure and function with RFdiffusion
    Joseph L. Watson, David Juergens et al. · 2023 · 2,306 citations · Free PDF
  7. Ultrafast one‐pass FASTQ data preprocessing, quality control, and deduplication using fastp
    Shifu Chen · 2023 · 2,139 citations
  8. Accurate proteome-wide missense variant effect prediction with AlphaMissense
    Jun Cheng, Guido Novati et al. · 2023 · 2,129 citations
  9. PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
    Antonino Glaviano, Aaron Song Chuan Foo et al. · 2023 · 2,095 citations · Free PDF
  10. AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences
    Mihály Váradi, Damian Bertoni et al. · 2023 · 2,030 citations
  11. Proksee: in-depth characterization and visualization of bacterial genomes
    Jason R Grant, Eric Enns et al. · 2023 · 1,898 citations
  12. MitoHiFi: a python pipeline for mitochondrial genome assembly from PacBio high fidelity reads
    Marcela Uliano‐Silva, João Gabriel R. N. Ferreira et al. · 2023 · 1,896 citations · Free PDF
  13. Plasma proteomic associations with genetics and health in the UK Biobank
    Benjamin B. Sun, Joshua Chiou et al. · 2023 · 1,804 citations · Free PDF
  14. g:Profiler—interoperable web service for functional enrichment analysis and gene identifier mapping (2023 update)
    Liis Kolberg, Uku Raudvere et al. · 2023 · 1,670 citations
  15. Hypoxic microenvironment in cancer: molecular mechanisms and therapeutic interventions
    Zhou Chen, Fangfang Han et al. · 2023 · 1,570 citations · Free PDF
  16. The Reactome Pathway Knowledgebase 2024
    Marija Orlic-Milacic, Deidre Beavers et al. · 2023 · 1,490 citations
  17. Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4
    Aitor Blanco‐Míguez, Francesco Beghini et al. · 2023 · 1,428 citations · Free PDF
  18. Gut microbiota, intestinal permeability, and systemic inflammation: a narrative review
    Federica Di Vincenzo, Angelo DEL GAUDIO et al. · 2023 · 1,371 citations · Free PDF
  19. Tree Visualization By One Table (tvBOT): a web application for visualizing, modifying and annotating phylogenetic trees
    Jianmin Xie, Yuerong Chen et al. · 2023 · 1,363 citations
  20. Angiogenic signaling pathways and anti-angiogenic therapy for cancer
    Zhenling Liu, Huanhuan Chen et al. · 2023 · 1,299 citations · Free PDF
  21. Next-Generation Sequencing Technology: Current Trends and Advancements
    Heena Satam, Kandarp Joshi et al. · 2023 · 1,272 citations · Free PDF
  22. Mitochondrial dynamics in health and disease: mechanisms and potential targets
    Wen Chen, Huakan Zhao et al. · 2023 · 1,267 citations · Free PDF
  23. Short-Chain Fatty-Acid-Producing Bacteria: Key Components of the Human Gut Microbiota
    William G. Fusco, Manuel Bernabeu et al. · 2023 · 1,244 citations · Free PDF
  24. Structural Mechanisms of NLRP3 Inflammasome Assembly and Activation
    Jianing Fu, Hao Wu · 2023 · 1,186 citations
  25. A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
    Zizhen Yao, Cindy T. J. van Velthoven et al. · 2023 · 1,177 citations · Free PDF

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