Most-cited Genetics and Biochemistry papers of 2020, with free PDFs

The 25 most-cited Genetics and Biochemistry research papers published in 2020, ranked by citations in OpenAlex, with their original abstracts and free PDFs where available.

1. IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era
   Bùi Quang Minh, Heiko A. Schmidt et al. · 2020 · 16,861 citations · Free PDF
2. The biology , function , and biomedical applications of exosomes
   Raghu K. Kalluri, Valerie S. LeBleu · 2020 · 10,681 citations
3. The mutational constraint spectrum quantified from variation in 141,456 humans
   Konrad J. Karczewski, Laurent C. Francioli et al. · 2020 · 9,490 citations · Free PDF
4. The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets
   Damian Szklarczyk, Annika L Gable et al. · 2020 · 8,105 citations
5. Pfam: The protein families database in 2021
   Jaina Mistry, Sara Chuguransky et al. · 2020 · 7,377 citations
6. U1 snRNP regulates cancer cell migration and invasion in vitro
   Jung‐Min Oh, Christopher C. Venters et al. · 2020 · 7,152 citations · Free PDF
7. UniProt: the universal protein knowledgebase in 2021
   Alex G. Bateman, Maria Jesus Martin et al. · 2020 · 6,435 citations
8. The GTEx Consortium atlas of genetic regulatory effects across human tissues
   François Aguet, Shankara K. Anand et al. · 2020 · 5,524 citations · Free PDF
9. KEGG: integrating viruses and cellular organisms
   Minoru I. Kanehisa, Miho Furumichi et al. · 2020 · 4,060 citations
10. GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes
    Jian‐Jun Jin, Wen-Bin Yu et al. · 2020 · 3,998 citations · Free PDF
11. Interaction between microbiota and immunity in health and disease
    Danping Zheng, Timur Liwinski et al. · 2020 · 3,925 citations · Free PDF
12. Merqury: reference-free quality, completeness, and phasing assessment for genome assemblies
    Arang Rhie, Brian P. Walenz et al. · 2020 · 3,657 citations · Free PDF
13. The Gene Ontology resource: enriching a GOld mine
    Seth J Carbon, Eric Douglass et al. · 2020 · 3,578 citations · Free PDF
14. Using SPAdes De Novo Assembler
    Andrey D. Prjibelski, Dmitry Antipov et al. · 2020 · 3,554 citations
15. The repertoire of mutational signatures in human cancer
    Ludmil B. Alexandrov, Jaegil Kim et al. · 2020 · 3,516 citations · Free PDF
16. ResFinder 4.0 for predictions of phenotypes from genotypes
    Valeria Bortolaia, Rolf Sommer Kaas et al. · 2020 · 3,375 citations
17. Pembrolizumab for Early Triple-Negative Breast Cancer
    Peter Schmid, Javier Cortés et al. · 2020 · 3,232 citations
18. Pan-cancer analysis of whole genomes
    Lauri A. Aaltonen, Federico Abascal et al. · 2020 · 3,102 citations · Free PDF
19. The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication
    Ygor Parladore Silva, Andressa Bernardi et al. · 2020 · 3,009 citations
20. Mitochondrial TCA cycle metabolites control physiology and disease
    Inmaculada Martínez‐Reyes, Navdeep S. Chandel · 2020 · 2,805 citations · Free PDF
21. GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes
    T. Rhyker Ranallo-Benavidez, Kamil S. Jaroň et al. · 2020 · 2,795 citations · Free PDF
22. Identifying and removing haplotypic duplication in primary genome assemblies
    Dengfeng Guan, Shane McCarthy et al. · 2020 · 2,767 citations · Free PDF
23. Metabolic reprogramming and cancer progression
    Brandon Faubert, Ashley Solmonson et al. · 2020 · 2,701 citations
24. BlobToolKit – Interactive Quality Assessment of Genome Assemblies
    RICHARD J. CHALLIS, Edward Richards et al. · 2020 · 2,653 citations · Free PDF
25. NCBI Taxonomy: a comprehensive update on curation, resources and tools
    Conrad L. Schoch, Stacy A. Ciufo et al. · 2020 · 2,628 citations

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