Most-cited Genetics and Biochemistry papers of 2018, with free PDFs

The 25 most-cited Genetics and Biochemistry research papers published in 2018, ranked by citations in OpenAlex, with their original abstracts and free PDFs where available.

1. MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms
   Sudhir Kumar, Glen Stecher et al. · 2018 · 37,738 citations
2. fastp: an ultra-fast all-in-one FASTQ preprocessor
   Shifu Chen, Yanqing Zhou et al. · 2018 · 29,614 citations · Free PDF
3. STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
   Damian Szklarczyk, Annika L. Gable et al. · 2018 · 17,862 citations
4. Minimap2: pairwise alignment for nucleotide sequences
   Heng Li · 2018 · 15,482 citations · Free PDF
5. SWISS-MODEL: homology modelling of protein structures and complexes
   Andrew Mark Waterhouse, Martino Bertoni et al. · 2018 · 13,184 citations
6. Posterior Summarization in Bayesian Phylogenetics Using Tracer 1.7
   Andrew Rambaut, Alexei J. Drummond et al. · 2018 · 11,159 citations · Free PDF
7. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
   Clotilde Théry, Kenneth Whitaker Witwer et al. · 2018 · 11,018 citations · Free PDF
8. ape 5.0: an environment for modern phylogenetics and evolutionary analyses in R
   Emmanuel Paradis, Klaus Peter Schliep · 2018 · 9,242 citations
9. The UK Biobank resource with deep phenotyping and genomic data
   Clare Bycroft, Colin Freeman et al. · 2018 · 8,970 citations · Free PDF
10. SCANPY: large-scale single-cell gene expression data analysis
    F. Alexander Wolf, Philipp Angerer et al. · 2018 · 8,879 citations · Free PDF
11. The MR-Base platform supports systematic causal inference across the human phenome
    Gibran Hemani, Jie Zheng et al. · 2018 · 7,993 citations
12. UniProt: a worldwide hub of protein knowledge
    The UniProt Consortium · 2018 · 7,771 citations
13. Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2’s q2-feature-classifier plugin
    Nicholas A. Bokulich, Benjamin D. Kaehler et al. · 2018 · 5,930 citations · Free PDF
14. High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries
    Chirag Jain, Luis M. Rodriguez‐R et al. · 2018 · 5,736 citations · Free PDF
15. Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation
    Jacob Anderson O’Brien, Heyam Hayder et al. · 2018 · 5,277 citations · Free PDF
16. eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses
    Jaime Huerta‐Cepas, Damian Szklarczyk et al. · 2018 · 4,993 citations
17. COSMIC: the Catalogue Of Somatic Mutations In Cancer
    John G. Tate, Sally Bamford et al. · 2018 · 4,876 citations
18. The Gene Ontology Resource: 20 years and still GOing strong
    Consortium, The Gene Ontology · 2018 · 4,792 citations
19. miRBase: from microRNA sequences to function
    Ana Kozomara, Maria Birgaoanu et al. · 2018 · 4,774 citations
20. New tools for automated high-resolution cryo-EM structure determination in RELION-3
    Jasenko Zivanov, Takanori Nakane et al. · 2018 · 4,713 citations · Free PDF
21. The Pfam protein families database in 2019
    Sara El-Gebali, Jaina Mistry et al. · 2018 · 4,634 citations
22. CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
    Janice S. Chen, Enbo Ma et al. · 2018 · 4,490 citations · Free PDF
23. Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians
    Neil M Davies, Michael Vaclav Holmes et al. · 2018 · 4,416 citations
24. Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
    Peter Schmid, Sylvia Adams et al. · 2018 · 4,359 citations
25. The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
    Annalisa Buniello, Jacqueline A. L. MacArthur et al. · 2018 · 4,069 citations

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