Most-cited Medicine papers of 2024, with free PDFs

The 25 most-cited Medicine research papers published in 2024, ranked by citations in OpenAlex, with their original abstracts and free PDFs where available.

  1. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
    Freddie Bray, Mathieu Laversanne et al. · 2024 · 26,323 citations
  2. Cancer statistics, 2024
    Rebecca L. Siegel, Angela N. Giaquinto et al. · 2024 · 9,433 citations
  3. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease
    Paul E. Stevens, Sofia Bano Ahmed et al. · 2024 · 8,342 citations
  4. 2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)
    Isabelle C. Van Gelder, Michiel Rienstra et al. · 2024 · 3,016 citations · Free PDF
  5. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
    Michael Brauer, Gregory A. Roth et al. · 2024 · 2,824 citations · Free PDF
  6. 2024 ESC Guidelines for the management of chronic coronary syndromes
    Christiaan J. Vrints, Felicita Andreotti et al. · 2024 · 2,778 citations
  7. Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup
    Clifford R. Jack, Jeffrey Scott Andrews et al. · 2024 · 2,728 citations
  8. 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association
    Seth Shay Martin, Aaron W. Aday et al. · 2024 · 2,654 citations
  9. 2024 Alzheimer's disease facts and figures
    2024 · 2,481 citations
  10. Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
    Nowell H Phelps, Rosie K. Singleton et al. · 2024 · 2,448 citations · Free PDF
  11. Cancer incidence and mortality in China, 2022
    Bingfeng Han, Rongshou Zheng et al. · 2024 · 2,242 citations
  12. EASL–EASD–EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)
    Frank Tacke, Paul M. Horn et al. · 2024 · 2,114 citations
  13. A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis
    Stephen A. Harrison, Pierre Bédossa et al. · 2024 · 2,007 citations
  14. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes
    Vlado Perkovic, Katherine R. Tuttle et al. · 2024 · 1,873 citations
  15. A Study to Evaluate Psychological Distress and Self-Esteem Among Patients with Hemodialysis
    Yogesh Kumar C - · 2024 · 1,745 citations · Free PDF
  16. World Medical Association Declaration of Helsinki
    World Medical Association · 2024 · 1,562 citations
  17. World Stroke Organization: Global Stroke Fact Sheet 2025
    Valery L. Feigin, Michael Brainin et al. · 2024 · 1,403 citations · Free PDF
  18. Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants
    Klaudia Jomová, Suliman Yousef Alomar et al. · 2024 · 1,397 citations · Free PDF
  19. 2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes—2025
    Nuha A. ElSayed, Rozalina Grubina McCoy et al. · 2024 · 1,340 citations
  20. CAT: a computational anatomy toolbox for the analysis of structural MRI data
    Christian Gaser, Robert Dahnke et al. · 2024 · 1,293 citations · Free PDF
  21. Editor's Choice -- European Society for Vascular Surgery (ESVS) 2024 Clinical Practice Guidelines on the Management of Abdominal Aorto-Iliac Artery Aneurysms
    Anders Wanhainen, Isabelle VAN HERZEELE et al. · 2024 · 1,205 citations · Free PDF
  22. Exploring treatment options in cancer: tumor treatment strategies
    Beilei Liu, Hongyu Zhou et al. · 2024 · 1,166 citations
  23. Recent advances in Alzheimer’s disease: mechanisms, clinical trials and new drug development strategies
    Jifa Zhang, Yinglu Zhang et al. · 2024 · 1,142 citations · Free PDF
  24. Enfortumab Vedotin and Pembrolizumab in Untreated Advanced Urothelial Cancer
    Thomas B. Powles, Begoña P. Valderrama et al. · 2024 · 1,097 citations
  25. Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects
    Mary E. Jensen, Avery J. Evans et al. · 2024 · 1,091 citations

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