Most-cited Medicine papers of 2023, with free PDFs

The 25 most-cited Medicine research papers published in 2023, ranked by citations in OpenAlex, with their original abstracts and free PDFs where available.

1. Cancer statistics, 2023
   Rebecca L. Siegel, Kimberly D. Miller et al. · 2023 · 16,246 citations
2. Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association
   Connie W. Tsao, Aaron W. Aday et al. · 2023 · 6,069 citations
3. 2023 ESC Guidelines for the management of acute coronary syndromes
   Robert A. Byrne, Xavier Rosselló et al. · 2023 · 5,182 citations
4. Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021
   Kanyin Liane Ong, Lauryn K Stafford et al. · 2023 · 4,681 citations · Free PDF
5. Performance of ChatGPT on USMLE: Potential for AI-assisted medical education using large language models
   Tiffany H. Kung, Morgan Cheatham et al. · 2023 · 4,100 citations · Free PDF
6. Large language models encode clinical knowledge
   Karan Singhal, Shekoofeh Azizi et al. · 2023 · 3,866 citations · Free PDF
7. Colorectal cancer statistics, 2023
   Rebecca L. Siegel, Nikita Sandeep Wagle et al. · 2023 · 3,770 citations
8. The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review
   Zobair M. Younossi, Pegah Golabi et al. · 2023 · 3,310 citations
9. A multisociety Delphi consensus statement on new fatty liver disease nomenclature
   Mary Eugenia Rinella, Jeffrey Victor Lazarus et al. · 2023 · 3,201 citations · Free PDF
10. 2023 Alzheimer's disease facts and figures
    2023 · 3,187 citations
11. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
    Abraham Michael Lincoff, Kirstine Brown‐Frandsen et al. · 2023 · 3,111 citations · Free PDF
12. Revolutionizing healthcare: the role of artificial intelligence in clinical practice
    Shuroug A. Alowais, Sahar S. Alghamdi et al. · 2023 · 3,106 citations · Free PDF
13. ChatGPT Utility in Healthcare Education, Research, and Practice: Systematic Review on the Promising Perspectives and Valid Concerns
    Malik Sallam · 2023 · 3,085 citations · Free PDF
14. A multisociety Delphi consensus statement on new fatty liver disease nomenclature
    Mary Eugenia Rinella, Jeffrey Victor Lazarus et al. · 2023 · 3,038 citations · Free PDF
15. Donanemab in Early Symptomatic Alzheimer Disease
    John Randall Sims, Jennifer A. Zimmer et al. · 2023 · 2,865 citations
16. 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
    José A. Joglar, Mina K. Chung et al. · 2023 · 2,753 citations · Free PDF
17. 2023 ESC Guidelines for the management of cardiomyopathies
    Elena Arbelo, Alexandros Protonotarios et al. · 2023 · 2,751 citations
18. Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging
    Klaudia Jomová, Renáta Raptová et al. · 2023 · 2,589 citations · Free PDF
19. AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
    Mary Eugenia Rinella, Brent A. Neuschwander‐Tetri et al. · 2023 · 2,586 citations
20. Comparing Physician and Artificial Intelligence Chatbot Responses to Patient Questions Posted to a Public Social Media Forum
    John W. Ayers, Adam Poliak et al. · 2023 · 2,568 citations
21. 2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
    Theresa A. McDonagh, Marco Metra et al. · 2023 · 2,416 citations · Free PDF
22. antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation
    Kai Blin, Simon Shaw et al. · 2023 · 2,314 citations · Free PDF
23. Global burden of liver disease: 2023 update
    Harshad C. Devarbhavi, Sumeet K. Asrani et al. · 2023 · 2,229 citations
24. Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association
    Chiadi E. Ndumele, Janani Rangaswami et al. · 2023 · 2,118 citations
25. How Does ChatGPT Perform on the United States Medical Licensing Examination (USMLE)? The Implications of Large Language Models for Medical Education and Knowledge Assessment
    Aidan Gilson, Conrad W. Safranek et al. · 2023 · 2,071 citations

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