Most-cited Neuroscience papers of 2016, with free PDFs

The 25 most-cited Neuroscience research papers published in 2016, ranked by citations in OpenAlex, with their original abstracts and free PDFs where available.

  1. Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy
    Shikshya Shrestha, Steven M. Offer · 2016 · 8,923 citations
  2. Cluster failure: Why fMRI inferences for spatial extent have inflated false-positive rates
    Anders Eklund, Thomas E. Nichols et al. · 2016 · 3,522 citations · Free PDF
  3. Complement and microglia mediate early synapse loss in Alzheimer mouse models
    Soyon Hong, Victoria F. Beja-Glasser et al. · 2016 · 3,317 citations
  4. The Human Brainnetome Atlas: A New Brain Atlas Based on Connectional Architecture
    Lingzhong Fan, Hai Li et al. · 2016 · 3,052 citations
  5. Brain Tumor Segmentation Using Convolutional Neural Networks in MRI Images
    Sérgio Pereira, Adriano B. Pinto et al. · 2016 · 2,749 citations
  6. Situating the default-mode network along a principal gradient of macroscale cortical organization
    Daniel S. Margulies, Satrajit Ghosh et al. · 2016 · 2,375 citations · Free PDF
  7. Neurobiologic Advances from the Brain Disease Model of Addiction
    Nora D. Volkow, George F. Koob et al. · 2016 · 1,995 citations
  8. Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2012
    Deborah Christensen, Jon Baio et al. · 2016 · 1,969 citations · Free PDF
  9. How neuroinflammation contributes to neurodegeneration
    Richard M. Ransohoff · 2016 · 1,961 citations
  10. New tools for studying microglia in the mouse and human CNS
    Mariko L. Bennett, F. Chris Bennett et al. · 2016 · 1,810 citations
  11. Use of NeuroEyeCoach™ to Improve Eye Movement Efficacy in Patients with Homonymous Visual Field Loss
    Arash Sahraie, Nicola Smania et al. · 2016 · 1,772 citations
  12. Neuroinflammation in Alzheimer's disease: Current evidence and future directions
    Valeria Calsolaro, Paul Edison · 2016 · 1,730 citations
  13. Melatonin as an antioxidant: under promises but over delivers
    Russel Joseph Reiter, Juan Carlos Mayo et al. · 2016 · 1,711 citations
  14. Neuroinflammation: the devil is in the details
    Damon J. DiSabato, Ning Quan et al. · 2016 · 1,627 citations
  15. Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density
    Kellie S. Gross, Dieter D. Brandner et al. · 2016 · 1,612 citations · Free PDF
  16. Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases
    Cláudia Saraiva, Catarina Praça et al. · 2016 · 1,595 citations
  17. The two‐process model of sleep regulation: a reappraisal
    Alexander A. Borbély, Serge Daan et al. · 2016 · 1,579 citations
  18. Annual Research Review: On the relations among self‐regulation, self‐control, executive functioning, effortful control, cognitive control, impulsivity, risk‐taking, and inhibition for developmental psychopathology
    Joel T. Nigg · 2016 · 1,519 citations
  19. Liking, wanting, and the incentive-sensitization theory of addiction.
    Kent C. Berridge, Terry E. Robinson · 2016 · 1,437 citations
  20. The theory of constructed emotion: an active inference account of interoception and categorization
    Lisa Feldman Barrett · 2016 · 1,434 citations
  21. Microglia in Physiology and Disease
    Susanne A. Wolf, H. W. G. M. Boddeke et al. · 2016 · 1,425 citations
  22. The dynamic functional connectome: State-of-the-art and perspectives
    Maria Giulia Preti, Thomas A. W. Bolton et al. · 2016 · 1,420 citations
  23. A Tutorial Review of Functional Connectivity Analysis Methods and Their Interpretational Pitfalls
    André M. Bastos, Jan‐Mathijs Schoffelen · 2016 · 1,329 citations · Free PDF
  24. Hearing Impairment and Cognitive Energy: The Framework for Understanding Effortful Listening (FUEL)
    Margaret Kathleen Pichora-Fuller, Sophia E. Kramer et al. · 2016 · 1,325 citations · Free PDF
  25. How to get statistically significant effects in any ERP experiment (and why you shouldn't)
    Steven J. Luck, Nicholas Gaspelin · 2016 · 1,224 citations

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