# Most-cited Medicine papers of 2023, with free PDFs

The 25 most-cited Medicine research papers published in 2023, ranked by citations in OpenAlex, with their original abstracts and free PDFs where available.

1. [Cancer statistics, 2023](https://nerdi.pages.dev/paper/W4315754639) · 16,246 citations
2. [Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association](https://nerdi.pages.dev/paper/W4211191293) · 6,069 citations
3. [2023 ESC Guidelines for the management of acute coronary syndromes](https://nerdi.pages.dev/paper/W4386153206) · 5,182 citations
4. [Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021](https://nerdi.pages.dev/paper/W4381799391) · 4,681 citations · Free PDF
5. [Performance of ChatGPT on USMLE: Potential for AI-assisted medical education using large language models](https://nerdi.pages.dev/paper/W4319662928) · 4,100 citations · Free PDF
6. [Large language models encode clinical knowledge](https://nerdi.pages.dev/paper/W4384071683) · 3,866 citations · Free PDF
7. [Colorectal cancer statistics, 2023](https://nerdi.pages.dev/paper/W4322719806) · 3,770 citations
8. [The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review](https://nerdi.pages.dev/paper/W4315619045) · 3,310 citations
9. [A multisociety Delphi consensus statement on new fatty liver disease nomenclature](https://nerdi.pages.dev/paper/W4381681857) · 3,201 citations · Free PDF
10. [2023 Alzheimer's disease facts and figures](https://nerdi.pages.dev/paper/W4324309277) · 3,187 citations
11. [Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes](https://nerdi.pages.dev/paper/W4388592674) · 3,111 citations · Free PDF
12. [Revolutionizing healthcare: the role of artificial intelligence in clinical practice](https://nerdi.pages.dev/paper/W4386958277) · 3,106 citations · Free PDF
13. [ChatGPT Utility in Healthcare Education, Research, and Practice: Systematic Review on the Promising Perspectives and Valid Concerns](https://nerdi.pages.dev/paper/W4327946446) · 3,085 citations · Free PDF
14. [A multisociety Delphi consensus statement on new fatty liver disease nomenclature](https://nerdi.pages.dev/paper/W4381893710) · 3,038 citations · Free PDF
15. [Donanemab in Early Symptomatic Alzheimer Disease](https://nerdi.pages.dev/paper/W4384522480) · 2,865 citations
16. [2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines](https://nerdi.pages.dev/paper/W4389166035) · 2,753 citations · Free PDF
17. [2023 ESC Guidelines for the management of cardiomyopathies](https://nerdi.pages.dev/paper/W4386152544) · 2,751 citations
18. [Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging](https://nerdi.pages.dev/paper/W4385999933) · 2,589 citations · Free PDF
19. [AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease](https://nerdi.pages.dev/paper/W4318923555) · 2,586 citations
20. [Comparing Physician and Artificial Intelligence Chatbot Responses to Patient Questions Posted to a Public Social Media Forum](https://nerdi.pages.dev/paper/W4367310920) · 2,568 citations
21. [2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure](https://nerdi.pages.dev/paper/W4386151215) · 2,416 citations · Free PDF
22. [antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation](https://nerdi.pages.dev/paper/W4368358469) · 2,314 citations · Free PDF
23. [Global burden of liver disease: 2023 update](https://nerdi.pages.dev/paper/W4361000000) · 2,229 citations
24. [Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association](https://nerdi.pages.dev/paper/W4387439311) · 2,118 citations
25. [How Does ChatGPT Perform on the United States Medical Licensing Examination (USMLE)? The Implications of Large Language Models for Medical Education and Knowledge Assessment](https://nerdi.pages.dev/paper/W4319460874) · 2,071 citations

Canonical page: https://nerdi.pages.dev/papers/medicine/most-cited-2023