# Most-cited Agriculture and Biology papers of 2021, with free PDFs

The 25 most-cited Agriculture and Biology research papers published in 2021, ranked by citations in OpenAlex, with their original abstracts and free PDFs where available.

1. [The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics](https://nerdi.pages.dev/paper/W4205948442) · 2,413 citations · Free PDF
2. [Drought Stress Impacts on Plants and Different Approaches to Alleviate Its Adverse Effects](https://nerdi.pages.dev/paper/W3125847321) · 1,982 citations · Free PDF
3. [The European Union One Health 2020 Zoonoses Report](https://nerdi.pages.dev/paper/W4200000976) · 1,579 citations
4. [Abiotic Stress and Reactive Oxygen Species: Generation, Signaling, and Defense Mechanisms](https://nerdi.pages.dev/paper/W3127184027) · 1,571 citations · Free PDF
5. [Impact of Climate Change on Agriculture and Its Mitigation Strategies: A Review](https://nerdi.pages.dev/paper/W3122928643) · 1,516 citations · Free PDF
6. [The Impact of Climate Change on Agricultural Insect Pests](https://nerdi.pages.dev/paper/W3162877622) · 1,428 citations · Free PDF
7. [Global Warming, Climate Change, and Environmental Pollution: Recipe for a Multifactorial Stress Combination Disaster](https://nerdi.pages.dev/paper/W3138105444) · 1,133 citations
8. [How biochar works, and when it doesn't: A review of mechanisms controlling soil and plant responses to biochar](https://nerdi.pages.dev/paper/W3185137361) · 1,070 citations
9. [Response Mechanism of Plants to Drought Stress](https://nerdi.pages.dev/paper/W3136889721) · 1,055 citations · Free PDF
10. [Regulation of Plant Responses to Salt Stress](https://nerdi.pages.dev/paper/W3157510358) · 1,039 citations · Free PDF
11. [Global predictions of primary soil salinization under changing climate in the 21st century](https://nerdi.pages.dev/paper/W3212566395) · 1,032 citations · Free PDF
12. [Plant diseases and pests detection based on deep learning: a review](https://nerdi.pages.dev/paper/W3130071898) · 1,016 citations · Free PDF
13. [Plant Disease Detection and Classification by Deep Learning—A Review](https://nerdi.pages.dev/paper/W3155966371) · 1,010 citations
14. [The Significance of Reactive Oxygen Species and Antioxidant Defense System in Plants: A Concise Overview](https://nerdi.pages.dev/paper/W3119010472) · 1,000 citations · Free PDF
15. [Recent Developments in Enzymatic Antioxidant Defence Mechanism in Plants with Special Reference to Abiotic Stress](https://nerdi.pages.dev/paper/W3150151527) · 995 citations · Free PDF
16. [Metabolism Characteristics of Lactic Acid Bacteria and the Expanding Applications in Food Industry](https://nerdi.pages.dev/paper/W3162566743) · 994 citations · Free PDF
17. [Towards Advances in Medicinal Plant Antimicrobial Activity: A Review Study on Challenges and Future Perspectives](https://nerdi.pages.dev/paper/W3201936720) · 993 citations · Free PDF
18. [The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on fermented foods](https://nerdi.pages.dev/paper/W3119286420) · 922 citations · Free PDF
19. [Anti-Inflammatory and Immunomodulatory Effects of Probiotics in Gut Inflammation: A Door to the Body](https://nerdi.pages.dev/paper/W3135522947) · 913 citations · Free PDF
20. [Machine Learning in Agriculture: A Comprehensive Updated Review](https://nerdi.pages.dev/paper/W3165319944) · 899 citations · Free PDF
21. [Plant Growth Promoting Rhizobacteria (PGPR) as Green Bioinoculants: Recent Developments, Constraints, and Prospects](https://nerdi.pages.dev/paper/W3123344217) · 898 citations · Free PDF
22. [Regulation of Reactive Oxygen Species and Antioxidant Defense in Plants under Salinity](https://nerdi.pages.dev/paper/W3197540311) · 876 citations · Free PDF
23. [Diversity of Synthetic Dyes from Textile Industries, Discharge Impacts and Treatment Methods](https://nerdi.pages.dev/paper/W3182829075) · 875 citations · Free PDF
24. [The persistent threat of emerging plant disease pandemics to global food security](https://nerdi.pages.dev/paper/W3163531312) · 828 citations
25. [Particulate organic matter as a functional soil component for persistent soil organic carbon](https://nerdi.pages.dev/paper/W3178178929) · 814 citations · Free PDF

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