# Target Trial Emulation

“Target Trial Emulation” (2022), by Miguel Ángel Hernán et al. Mathematics research paper. Original abstract below, unchanged. No free PDF was found.

- Authors: Miguel Ángel Hernán, Wei Wang, David E. Leaf
- Published: December 12, 2022
- Field: Mathematics
- DOI: https://doi.org/10.1001/jama.2022.21383
- Source: https://doi.org/10.1001/jama.2022.21383

## Abstract

This Guide to Statistics and Methods describes the use of target trial emulation to design an observational study so it preserves the advantages of a randomized clinical trial, points out the limitations of the method, and provides an example of its use.

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