# Zwitterionic Biomaterials

“Zwitterionic Biomaterials” (2022), by Qingsi Li et al. Materials Science research paper. Original abstract below, unchanged. No free PDF was found.

- Authors: Qingsi Li, Chiyu Wen, Jing Yang, Xianchi Zhou, Yingnan Zhu, Jie Zheng, Gang Cheng, Jie Bai, Tong Xu, Jian Ji et al.
- Published: October 6, 2022
- Field: Materials Science
- DOI: https://doi.org/10.1021/acs.chemrev.2c00344
- Source: https://doi.org/10.1021/acs.chemrev.2c00344

## Abstract

The term "zwitterionic polymers" refers to polymers that bear a pair of oppositely charged groups in their repeating units. When these oppositely charged groups are equally distributed at the molecular level, the molecules exhibit an overall neutral charge with a strong hydration effect via ionic solvation. The strong hydration effect constitutes the foundation of a series of exceptional properties of zwitterionic materials, including resistance to protein adsorption, lubrication at interfaces, promotion of protein stabilities, antifreezing in solutions, etc. As a result, zwitterionic materials have drawn great attention in biomedical and engineering applications in recent years. In this review, we give a comprehensive and panoramic overview of zwitterionic materials, covering the fundamentals of hydration and nonfouling behaviors, different types of zwitterionic surfaces and polymers, and their biomedical applications.

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