“ColabFold: making protein folding accessible to all” (2022), by Milot Mirdita et al. Genetics and Biochemistry research paper. Original abstract below, unchanged. A free PDF is available.

ColabFold: making protein folding accessible to all

Milot Mirdita, Konstantin Schütze, Yoshitaka Moriwaki et al. · May 30, 2022 · Genetics and Biochemistry

Abstract

ColabFold offers accelerated prediction of protein structures and complexes by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFold's 40-60-fold faster search and optimized model utilization enables prediction of close to 1,000 structures per day on a server with one graphics processing unit. Coupled with Google Colaboratory, ColabFold becomes a free and accessible platform for protein folding. ColabFold is open-source software available at https://github.com/sokrypton/ColabFold and its novel environmental databases are available at https://colabfold.mmseqs.com .

Free PDF DOI: 10.1038/s41592-022-01488-1