# A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells

“A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells” (2021), by Sijin Cheng et al. Immunology and Microbiology research paper. Original abstract below, unchanged. No free PDF was found.

- Authors: Sijin Cheng, Ziyi Li, Ranran Gao, Baocai Xing, Yunong Gao, Yu Yang, Shishang Qin, Lei Zhang, Hanqiang Ouyang, Peng Du et al.
- Published: February 1, 2021
- Field: Immunology and Microbiology
- DOI: https://doi.org/10.1016/j.cell.2021.01.010
- Source: https://doi.org/10.1016/j.cell.2021.01.010

## Abstract

cDCs revealed their differences in transcription factors and external stimulus. Additionally, pro-angiogenic tumor-associated macrophages (TAMs) were characterized with diverse markers across different cancer types, and the composition of TIMs appeared to be associated with certain features of somatic mutations and gene expressions. Our results provide a systematic view of the highly heterogeneous TIMs and suggest future avenues for rational, targeted immunotherapies.

Canonical page: https://nerdi.pages.dev/paper/W3126902084
Read three real papers a day in Nerdi (iPhone): https://apps.apple.com/app/apple-store/id6813826387?pt=128757794&ct=web-paper&mt=8