# A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications

“A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications” (2020), by Nagaraju Kerru et al. Chemistry research paper. Original abstract below, unchanged. A free PDF is available.

- Authors: Nagaraju Kerru, Lalitha Gummidi, Suresh Maddila, Kranthi Kumar Gangu, Sreekantha Babu Jonnalagadda
- Published: April 20, 2020
- Field: Chemistry
- DOI: https://doi.org/10.3390/molecules25081909
- Free PDF: https://www.mdpi.com/1420-3049/25/8/1909/pdf?version=1587883935

## Abstract

The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing heterocyclic moieties. In the forthcoming decade, a much greater share of new nitrogen-based pharmaceuticals is anticipated. Many new nitrogen-based heterocycles have been designed. The number of novel N-heterocyclic moieties with significant physiological properties and promising applications in medicinal chemistry is ever-growing. In this review, we consolidate the recent advances on novel nitrogen-containing heterocycles and their distinct biological activities, reported over the past one year (2019 to early 2020). This review highlights the trends in the use of nitrogen-based moieties in drug design and the development of different potent and competent candidates against various diseases.

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