# New Strategies for the Transition-Metal Catalyzed Synthesis of Aliphatic Amines

“New Strategies for the Transition-Metal Catalyzed Synthesis of Aliphatic Amines” (2020), by Aaron Trowbridge et al. Chemistry research paper. Original abstract below, unchanged. No free PDF was found.

- Authors: Aaron Trowbridge, Scarlett M. Walton, Matthew J. Gaunt
- Published: February 17, 2020
- Field: Chemistry
- DOI: https://doi.org/10.1021/acs.chemrev.9b00462
- Source: https://doi.org/10.1021/acs.chemrev.9b00462

## Abstract

Transition-metal catalyzed reactions that are able to construct complex aliphatic amines from simple, readily available feedstocks have become a cornerstone of modern synthetic organic chemistry. In light of the ever-increasing importance of aliphatic amines across the range of chemical sciences, this review aims to provide a concise overview of modern transition-metal catalyzed approaches to alkylamine synthesis and their functionalization. Selected examples of amine bond forming reactions include: (a) hydroamination and hydroaminoalkylation, (b) transition-metal catalyzed C(sp3)–H functionalization, and (c) transition-metal catalyzed visible-light-mediated light photoredox catalysis.

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