# Improved metagenomic analysis with Kraken 2

“Improved metagenomic analysis with Kraken 2” (2019), by Derrick E. Wood et al. Genetics and Biochemistry research paper. Original abstract below, unchanged. A free PDF is available.

- Authors: Derrick E. Wood, Jennifer Lu, Ben Langmead
- Published: November 28, 2019
- Field: Genetics and Biochemistry
- DOI: https://doi.org/10.1186/s13059-019-1891-0
- Free PDF: https://genomebiology.biomedcentral.com/counter/pdf/10.1186/s13059-019-1891-0

## Abstract

Although Kraken's k-mer-based approach provides a fast taxonomic classification of metagenomic sequence data, its large memory requirements can be limiting for some applications. Kraken 2 improves upon Kraken 1 by reducing memory usage by 85%, allowing greater amounts of reference genomic data to be used, while maintaining high accuracy and increasing speed fivefold. Kraken 2 also introduces a translated search mode, providing increased sensitivity in viral metagenomics analysis.

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