“Global increase and geographic convergence in antibiotic consumption between 2000 and 2015” (2018), by Eili Y. Klein et al. Immunology and Microbiology research paper. Original abstract below, unchanged. No free PDF was found.

Global increase and geographic convergence in antibiotic consumption between 2000 and 2015

Eili Y. Klein, Thomas P. Van Boeckel, Elena M. Martinez et al. · March 26, 2018 · Immunology and Microbiology

Abstract

= 0.004). In high-income countries (HICs), although overall consumption increased modestly, DDDs per 1,000 inhabitants per day fell 4%, and there was no correlation with GDPPC. Of particular concern was the rapid increase in the use of last-resort compounds, both in HICs and LMICs, such as glycylcyclines, oxazolidinones, carbapenems, and polymyxins. Projections of global antibiotic consumption in 2030, assuming no policy changes, were up to 200% higher than the 42 billion DDDs estimated in 2015. Although antibiotic consumption rates in most LMICs remain lower than in HICs despite higher bacterial disease burden, consumption in LMICs is rapidly converging to rates similar to HICs. Reducing global consumption is critical for reducing the threat of antibiotic resistance, but reduction efforts must balance access limitations in LMICs and take account of local and global resistance patterns.

Source page DOI: 10.1073/pnas.1717295115