“Recent Advances in Radical C–H Activation/Radical Cross-Coupling” (2017), by Hong Yi et al. Chemistry research paper. Original abstract below, unchanged. No free PDF was found.

Recent Advances in Radical C–H Activation/Radical Cross-Coupling

Hong Yi, Guoting Zhang, Huamin Wang et al. · June 22, 2017 · Chemistry

Abstract

Research and industrial interest in radical C-H activation/radical cross-coupling chemistry has continuously grown over the past few decades. These reactions offer fascinating and unconventional approaches toward connecting molecular fragments with high atom- and step-economy that are often complementary to traditional methods. Success in this area of research was made possible through the development of photocatalysis and first-row transition metal catalysis along with the use of peroxides as radical initiators. This Review provides a brief and concise overview of the current status and latest methodologies using radicals or radical cations as key intermediates produced via radical C-H activation. This Review includes radical addition, radical cascade cyclization, radical/radical cross-coupling, coupling of radicals with M-R groups, and coupling of radical cations with nucleophiles (Nu).

Source page DOI: 10.1021/acs.chemrev.6b00620