# The Halogen Bond

“The Halogen Bond” (2016), by Gabriella Cavallo et al. Chemistry research paper. Original abstract below, unchanged. No free PDF was found.

- Authors: Gabriella Cavallo, Pierangelo Metrangolo, Roberto Milani, Tullio Pilati, Arri Priimägi, Giuseppe Resnati, Giancarlo Terraneo
- Published: January 26, 2016
- Field: Chemistry
- DOI: https://doi.org/10.1021/acs.chemrev.5b00484
- Source: https://doi.org/10.1021/acs.chemrev.5b00484

## Abstract

The halogen bond occurs when there is evidence of a net attractive interaction between an electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic region in another, or the same, molecular entity. In this fairly extensive review, after a brief history of the interaction, we will provide the reader with a snapshot of where the research on the halogen bond is now, and, perhaps, where it is going. The specific advantages brought up by a design based on the use of the halogen bond will be demonstrated in quite different fields spanning from material sciences to biomolecular recognition and drug design.

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