# Neural Circuitry of Anxiety: Evidence from Structural and Functional Neuroimaging Studies

“Neural Circuitry of Anxiety: Evidence from Structural and Functional Neuroimaging Studies” (2025), by Paul A. Cannistraro et al. Psychology research paper. Original abstract below, unchanged. No free PDF was found.

- Authors: Paul A. Cannistraro, Scott L. Rauch, and Scott L. Rauch, MD
- Published: August 12, 2025
- Field: Psychology
- DOI: https://doi.org/10.64719/pb.4161
- Source: https://doi.org/10.64719/pb.4161

## Abstract

Present understanding of the neural circuitry of anxiety has come from a variety of sources, including animal, clinical, and most recently, neuroimaging studies. Evidence from these sources has converged to form a translational bridge from animal models to human pathophysiology. In particular, the classical fear conditioning paradigm has served as a foundation for this bridge. Proposed models for the neural circuitry of normal anxiety as well as the anxiety disorders are discussed. A brief review of specific findings from neuroimaging studies of posttraumatic stress disorder, specific phobia, social phobia, obsessive-compulsive disorder, and generalized anxiety disorder is also provided.

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